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When it comes to the gut, apigenin “affects Enterococcus caccae cell wall/membrane synthesis and increases the incidence of protein misfolding… Bacteroides galacturonicus growth was also inhibited by apigenin…[and] apigenin promoted overall growth and diversity, lowered Firmicutes to Bacteroidetes ratio, and promoted production of short chain fatty acids, including butyrate, which is associated with health” (Wang et al., 2017)